Peer reviewed:

27) Jevans, B., Cooper, F., Fatieieva, Y., Gogolou, A., Kang Y-N., Restuadi, R., Vanden Bergh, P., Adameyko, I., Thapar, N., Andrews, P.,  De Coppi, P., Tsakiridis, A.*, McCann*, C. (2024) Human enteric nervous system progenitor transplantation restores functional responses in Hirschsprung Disease patient-derived tissue. Gut. 2024 May 30:gutjnl-2023-331532.

*joint corresponding authors

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26) Saldana-Guerrero, I.M., Montano-Gutierrez, L., Boswell, K., Hafemeister, C., Pool, E., Shaw, L.E., Stavish, D., Lea, R.A., Wernig-Zorc, S., Bozsaky, E., Fetahu, I.S., Zoescher, P.,  Pötschger, U., Bernkopf, M.,Wenninger-Weinzierl, A., Sturtzel, C., Souilhol, C., Tarelli, S., Shoeb, M.R.,  Bozatzi, P., Rados, M., Guarini, M., Buri, M.C., Weninger, W., Putz, E.M., Huang, M., Ladenstein, R., Andrews, P.W., Barbaric, I., Cresswell, G.D., Bryant, H.E., Distel, M., Chesler, L., Taschner-Mandl, S., Farlik, M., Tsakiridis, A*., Halbritter, F*. (2024)  A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations. Nat Commun 15(1):3745. doi: 10.1038/s41467-024-47945-7.

*joint corresponding authors

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25) Cooper, F*.,  Souilhol, C., Haston, C. Gray, S., Boswell, K.,  Gogolou, A., Frith, T.,  Stavish, D., James, B.M.,  Bose, D.A.,  Dale, J.K., Tsakiridis, A*. (2023) Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors.  Development 2024 Jan 12:dev.202098. doi: 10.1242/dev.202098. Online ahead of print.

*joint corresponding authors

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24) Gogolou, A., Souilhol, C., Granata, I., Wymeersch, F.J., Manipur, I., Wind, M., Frith, T. J. R., Guarini, M., Bertero, A., Bock, C., Halbritter, F., Takasato, M., Guarracino, M. R.,Tsakiridis, A. (2022). Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor. eLife. 11:e74263. doi: 10.7554/eLife.74263. 

 

23)  Cooper, F. & Tsakiridis, A. (2022). Towards clinical applications of in vitro-derived axial progenitors. Dev Biol. 489:110-117. doi: 10.1016/j.ydbio.2022.06.006. 

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22) Cooper, F. & Tsakiridis, A. (2022). Shaping axial identity during human pluripotent stem cell differentiation to neural crest cells. Biochem Soc Trans (2022) BST20211152

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21) Wind, M. & Tsakiridis A. (2021).  In Vitro Generation of Posterior Motor Neurons from Human Pluripotent Stem Cells. Curr Protoc. 2021 Sep;1(9):e244. doi: 10.1002/cpz1.244.

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20) Gogolou, A., Frith, T.J.R, Tsakiridis A. (2021). Generating Enteric Nervous System Progenitors from Human Pluripotent Stem Cells. Current Protocols, 1, e137. doi: 10.1002/cpz1.137.

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19) Wind, M., Gogolou, A., Manipur, I., Granata, I., Butler, L., Andrews, P. W., Barbaric, I., Ke, N., Guarracino, M. R., Placzek, M., Tsakiridis, A. (2021). Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives. Development.  Mar 23;148(6):dev194415. doi: 10.1242/dev.194415.

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18) Wymeersch, F.J., Wilson, V., Tsakiridis, A. (2021). Understanding axial progenitor biology in vivo and in vitro. Development, 148: dev180612 doi: 10.1242/dev.180612.

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17) Frith, T.J.R*, Gogolou, A., Hackland, J.O.S., Hewitt, Z.A, Moore, H.D., Barbacic, I., Thapar, N., Burns, A., Andrews, P.W.A., Tsakiridis, A*., McCann, C*. (2020) Retinoic acid accelerates the specification of enteric neural progenitors from in vitro-derived neural crest. Stem Cell Reports. DOI:  https://doi.org/10.1016/j.stemcr.2020.07.024

*joint corresponding authors

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16) Ruske, L.J., Kursawe, J., Tsakiridis, A., Wilson, V., Fletcher, A.G., Blythe, R.A., Schumacher, L.J. (2020) Coupled differentiation and division of embryonic stem cells inferred from clonal snapshots.    Phys. Biol.  DOI: https://doi.org/10.1088/1478-3975/aba041

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15) Frith, T.J.R. & Tsakiridis, A. (2019) Efficient generation of trunk neural crest and sympathetic neurons from human pluripotent stem cells via a neuromesodermal axial progenitor intermediate. Current Protocols in Stem Cell Biology. Curr Protoc Stem Cell Biol. 2019 Jun;49(1):e81. doi: 10.1002/cpsc.81. Epub 2019 Jan 28.

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14) Sutherland, l., Ruhe, M., Gattegno, D., Mann, K., Greaves, J., Koscielniak, M., Meek, S., Lu, Z., Waterfall, M., Taylor, R., Tsakiridis, A., Brown, H., Maciver, S., Joshi, A., Clinton, M., Chamberlain, L., Smith, A., Burdon, T. (2018). LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein. J Cell Sci. 2018 131: jcs222257 doi: 10.1242/jcs.222257.

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13)  Frith, T.J.R., Granata, I., Wind, M., Stout, E., Thompson, O., Neumman, K., Stavish, D., Heath, P.R., Hackland, J.O.S., Ortmann, D., Anastassiadis, K., Gouti, M., Briscoe, J., Wilson, V., Johnson, SL., Placzek, M., Guarracino, M.R., Andrews, P.W.A., Tsakiridis, A. (2018). Human axial progenitors generate trunk neural crest cells in vitro. Elife. 2018 Aug 10;7. pii: e35786. doi: 10.7554/eLife.35786. [Epub ahead of print].

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12) Lopez-Yrigoyen, M., Fizanza, A., Cassetta, L., Axton, R.A., Taylor, H., Meseguer-Rippolles, J., Tsakiridis, A., Wilson, V., Hay, D., Pollard, J.W. & Forrester, L.M. (2018). A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and in vivo tracking of therapeutic cells. Philos Trans R Soc Lond B Biol Sci. DOI: 10.1098/rstb.2017.0219.

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11)  Economou, C*., Tsakiridis, A*, Wymeersch, F., Gordon-Keylock, S., Dewhurst, R. E., Medvinsky, A., Smith, A. J. H. & Wilson, V. (2015). Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation. BMC Dev Biol 15:35. 

*joint first authors

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10) Tsakiridis, A* & Wilson, V*. (2015). Assessing the bipotency of in vitro-derived neuromesodermal progenitors [v2; ref status: indexed, http://f1000r.es/5p3] F1000Research 2015, 4:100 (doi: 10.12688/f1000research.6345.2).

*joint corresponding authors

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9) Gouti, M*., Tsakiridis, A*., Wymeersch, F., Huang, Y., Kleinjung, J., Wilson, V. & Briscoe, J. (2014). In vitro generation of neuromesodermal progenitors reveals distinct roles for Wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PloS Biology. Aug 26;12(8):e1001937. doi: 10.1371/journal.pbio.1001937. eCollection 2014 Aug.

*joint first authors

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8) Tsakiridis, A*., Huang, Y., Blin, G., Skylaki, S., Wymeersch, F., Osorno, R., Economou, C., Karagianni, E., Zhao, S., Lowell, S. & Wilson, V*. (2014). Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors. Development 141, 1209-1221.

*joint corresponding authors

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7) Huang, Y., Osorno, R., Tsakiridis, A. & Wilson, V. (2012). The in vivo differentiation potential of epiblast stem cells revealed by chimeric embryo formation. Cell Reports 2, 1571-1578.

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6) Osorno, R*., Tsakiridis, A*., Wong, F., Cambray, N., Economou, C., Wilkie, R., Blin, G., Scotting, P. J., Chambers, I. & Wilson, V. (2012). The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression. Development 139, 2288-2298.

*joint first authors

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5) Brickman, J.M., Tsakiridis, A., To, C. & Stanford, W.L. (2010). A wider context for gene trap mutagenesis. Methods Enzymol. 477, 271-95.

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4) Tsakiridis, A., Tzouanakou, E., Rahman, A., Colby, D., Axton, R., Chambers, I., Wilson, V., Forrester, L. & Brickman, J.M. (2009). Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells. Nucleic Acids Res. 37, e129.

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3) Tsakiridis, A., Alexander, L.M., Gennet, N., Livigni, A., Sanchez-Martin, R.M., Li, M., Bradley, M. & Brickman, J.M. (2009). Microsphere-based tracing and molecular delivery in embryonic stem cells. Biomaterials 30, 5853-61.

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2) Sanchez-Martin, R.M., Alexander, L.M., Muzerelle, M., Cardenas-Maestre, J.M., Tsakiridis, A., Brickman J.M. & Bradley, M. (2009). Microsphere-mediated protein delivery into cells. Chembiochem. 10, 1453-6.

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1) Tsakiridis, A., Tzouanacou, E., Larralde, O., Watts, T.M., Wilson, V., Forrester, L. & Brickman, J.M. (2007). A novel triple fusion reporter system for use in gene trap mutagenesis. Genesis 45, 353-360.

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Preprints:

 

1) Butler, L., Adamson, K.I., Johnson, S.L., Jestice, L., Price, C.J., Stavish, D., Pooranachandran, N., Tsakiridis, A., Grierson, A., Barbaric, I. (2022). HDAC6 inhibition partially alleviates mitochondrial trafficking defects and restores motor function in human motor neuron and zebrafish models of Charcot-Marie-Tooth Disease Type 2A. bioRxiv. doi: https://doi.org/10.1101/2022.07.05.498819

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Lab in the News:

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• Understanding the genetic roots of aggressive childhood cancer: Research aims to improve Neuroblastoma treatment (6/3/2025).

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• Important step forward in stem cell therapy for rare bowel disease (1/7/2024).

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• Stem cells provide new insight into genetic pathway of childhood cancer (13/5/2024).​

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• Lab Meeting with the Tsakiridis Lab. The Node (4/4/2024).

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• The people behind the papers – Fay Cooper and Anestis Tsakiridis (2024) Development (2024) 151 (3): dev202709. 

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• "Three cutting-edge projects funded into childhood neuroblastoma". Little Princess Trust (24/1/2024).

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• What are the six main types of childhood cancer research? CCLG (27/2/2023). 

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• "Research Focus – An interview with Dr Anestis Tsakiridis". CCLG (27/8/2020).