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Peer reviewed:

27) Jevans, B., Cooper, F., Fatieieva, Y., Gogolou, A., Kang Y-N., Restuadi, R., Vanden Bergh, P., Adameyko, I., Thapar, N., Andrews, P.,  De Coppi, P., Tsakiridis, A.*, Conor J McCann*. (2024) Human enteric nervous system progenitor transplantation restores functional responses in Hirschsprung Disease patient-derived tissue. Gut. 2024 May 30:gutjnl-2023-331532.

*joint corresponding authors

26) Saldana-Guerrero, I.M., Montano-Gutierrez, L., Boswell, K., Hafemeister, C., Pool, E., Shaw, L.E., Stavish, D., Lea, R.A., Wernig-Zorc, S., Bozsaky, E., Fetahu, I.S., Zoescher, P.,  Pötschger, U., Bernkopf, M.,Wenninger-Weinzierl, A., Sturtzel, C., Souilhol, C.Tarelli, S., Shoeb, M.R.,  Bozatzi, P., Rados, M., Guarini, M., Buri, M.C., Weninger, W., Putz, E.M., Huang, M., Ladenstein, R., Andrews, P.W., Barbaric, I., Cresswell, G.D., Bryant, H.E., Distel, M., Chesler, L., Taschner-Mandl, S., Farlik, M., Tsakiridis, A*., Halbritter, F*. (2024)  A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations. Nat Commun 15(1):3745. doi: 10.1038/s41467-024-47945-7.

*joint corresponding authors

25) Cooper, F*.,  Souilhol, C., Haston, C. Gray, S., Boswell, K.,  Gogolou, A., Frith, T.,  Stavish, D., James, B.M.,  Bose, D.A.,  Dale, J.K., Tsakiridis, A*. (2023) Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors.  Development 2024 Jan 12:dev.202098. doi: 10.1242/dev.202098. Online ahead of print.

*joint corresponding authors

24) Gogolou, A., Souilhol, C., Granata, I., Wymeersch, F.J., Manipur, I., Wind, M., Frith, T. J. R., Guarini, M., Bertero, A., Bock, C., Halbritter, F., Takasato, M., Guarracino, M. R.,Tsakiridis, A. (2022). Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor. eLife. 11:e74263. doi: 10.7554/eLife.74263. 


23)  Cooper, F. & Tsakiridis, A. (2022). Towards clinical applications of in vitro-derived axial progenitors. Dev Biol. 489:110-117. doi: 10.1016/j.ydbio.2022.06.006. 

22) Cooper, F. & Tsakiridis, A. (2022). Shaping axial identity during human pluripotent stem cell differentiation to neural crest cells. Biochem Soc Trans (2022) BST20211152

21) Wind, M. & Tsakiridis A. (2021).  In Vitro Generation of Posterior Motor Neurons from Human Pluripotent Stem Cells. Curr Protoc. 2021 Sep;1(9):e244. doi: 10.1002/cpz1.244.

20) Gogolou, A.Frith, T.J.R, Tsakiridis A. (2021). Generating Enteric Nervous System Progenitors from Human Pluripotent Stem Cells. Current Protocols, 1, e137. doi: 10.1002/cpz1.137.

19) Wind, M., Gogolou, A., Manipur, I., Granata, I., Butler, L., Andrews, P. W., Barbaric, I., Ke, N., Guarracino, M. R., Placzek, M., Tsakiridis, A. (2021). Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives. Development.  Mar 23;148(6):dev194415. doi: 10.1242/dev.194415.

18) Wymeersch, F.J., Wilson, V., Tsakiridis, A. (2021). Understanding axial progenitor biology in vivo and in vitro. Development, 148: dev180612 doi: 10.1242/dev.180612.

17) Frith, T.J.R*, Gogolou, A., Hackland, J.O.S., Hewitt, Z.A, Moore, H.D., Barbacic, I., Thapar, N., Burns, A., Andrews, P.W.A., Tsakiridis, A*., McCann, C*. (2020) Retinoic acid accelerates the specification of enteric neural progenitors from in vitro-derived neural crest. Stem Cell Reports. DOI:

*joint corresponding authors

16) Ruske, L.J., Kursawe, J., Tsakiridis, A., Wilson, V., Fletcher, A.G., Blythe, R.A., Schumacher, L.J. (2020) Coupled differentiation and division of embryonic stem cells inferred from clonal snapshots.    Phys. Biol.  DOI:

15) Frith, T.J.R. & Tsakiridis, A. (2019) Efficient generation of trunk neural crest and sympathetic neurons from human pluripotent stem cells via a neuromesodermal axial progenitor intermediate. Current Protocols in Stem Cell Biology. Curr Protoc Stem Cell Biol. 2019 Jun;49(1):e81. doi: 10.1002/cpsc.81. Epub 2019 Jan 28.

14) Sutherland, l., Ruhe, M., Gattegno, D., Mann, K., Greaves, J., Koscielniak, M., Meek, S., Lu, Z., Waterfall, M., Taylor, R., Tsakiridis, A., Brown, H., Maciver, S., Joshi, A., Clinton, M., Chamberlain, L., Smith, A., Burdon, T. (2018). LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein. J Cell Sci. 2018 131: jcs222257 doi: 10.1242/jcs.222257.

13)  Frith, T.J.R., Granata, I., Wind, M., Stout, E., Thompson, O., Neumman, K., Stavish, D., Heath, P.R., Hackland, J.O.S., Ortmann, D., Anastassiadis, K., Gouti, M., Briscoe, J., Wilson, V., Johnson, SL., Placzek, M., Guarracino, M.R., Andrews, P.W.A., Tsakiridis, A. (2018). Human axial progenitors generate trunk neural crest cells in vitro. Elife. 2018 Aug 10;7. pii: e35786. doi: 10.7554/eLife.35786. [Epub ahead of print].

12) Lopez-Yrigoyen, M., Fizanza, A., Cassetta, L., Axton, R.A., Taylor, H., Meseguer-Rippolles, J., Tsakiridis, A., Wilson, V., Hay, D., Pollard, J.W. & Forrester, L.M. (2018). A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and in vivo tracking of therapeutic cells. Philos Trans R Soc Lond B Biol Sci. DOI: 10.1098/rstb.2017.0219.

11)  Economou, C*., Tsakiridis, A*, Wymeersch, F., Gordon-Keylock, S., Dewhurst, R. E., Medvinsky, A., Smith, A. J. H. & Wilson, V. (2015). Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation. BMC Dev Biol 15:35. 

*joint first authors

10) Tsakiridis, A* & Wilson, V*. (2015). Assessing the bipotency of in vitro-derived neuromesodermal progenitors [v2; ref status: indexed,] F1000Research 2015, 4:100 (doi: 10.12688/f1000research.6345.2).

*joint corresponding authors

9) Gouti, M*., Tsakiridis, A*., Wymeersch, F., Huang, Y., Kleinjung, J., Wilson, V. & Briscoe, J. (2014). In vitro generation of neuromesodermal progenitors reveals distinct roles for Wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PloS Biology. Aug 26;12(8):e1001937. doi: 10.1371/journal.pbio.1001937. eCollection 2014 Aug.

*joint first authors

8) Tsakiridis, A*., Huang, Y., Blin, G., Skylaki, S., Wymeersch, F., Osorno, R., Economou, C., Karagianni, E., Zhao, S., Lowell, S. & Wilson, V*. (2014). Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors. Development 141, 1209-1221.

*joint corresponding authors

7) Huang, Y., Osorno, R., Tsakiridis, A. & Wilson, V. (2012). The in vivo differentiation potential of epiblast stem cells revealed by chimeric embryo formation. Cell Reports 2, 1571-1578.

6) Osorno, R*., Tsakiridis, A*., Wong, F., Cambray, N., Economou, C., Wilkie, R., Blin, G., Scotting, P. J., Chambers, I. & Wilson, V. (2012). The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression. Development 139, 2288-2298.

*joint first authors

5) Brickman, J.M., Tsakiridis, A., To, C. & Stanford, W.L. (2010). A wider context for gene trap mutagenesis. Methods Enzymol. 477, 271-95.

4) Tsakiridis, A., Tzouanakou, E., Rahman, A., Colby, D., Axton, R., Chambers, I., Wilson, V., Forrester, L. & Brickman, J.M. (2009). Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells. Nucleic Acids Res. 37, e129.

3) Tsakiridis, A., Alexander, L.M., Gennet, N., Livigni, A., Sanchez-Martin, R.M., Li, M., Bradley, M. & Brickman, J.M. (2009). Microsphere-based tracing and molecular delivery in embryonic stem cells. Biomaterials 30, 5853-61.

2) Sanchez-Martin, R.M., Alexander, L.M., Muzerelle, M., Cardenas-Maestre, J.M., Tsakiridis, A., Brickman J.M. & Bradley, M. (2009). Microsphere-mediated protein delivery into cells. Chembiochem. 10, 1453-6.

1) Tsakiridis, A., Tzouanacou, E., Larralde, O., Watts, T.M., Wilson, V., Forrester, L. & Brickman, J.M. (2007). A novel triple fusion reporter system for use in gene trap mutagenesis. Genesis 45, 353-360.



1) Butler, L., Adamson, K.I., Johnson, S.L., Jestice, L., Price, C.J., Stavish, D., Pooranachandran, N., Tsakiridis, A., Grierson, A., Barbaric, I. (2022). HDAC6 inhibition partially alleviates mitochondrial trafficking defects and restores motor function in human motor neuron and zebrafish models of Charcot-Marie-Tooth Disease Type 2A. bioRxiv. doi:

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